![]() ![]() On the other hand, translation is the process of producing an amino acid sequence of a protein from a mRNA molecule. Primarily, transcription is the process of producing a mRNA molecule from a DNA template of a gene. We can identify the difference between transcription and translation based on several factors such as a template, raw material, location, product, enzymes involved, etc. Transcription and translation are two different steps of gene expression. What is the Difference Between Transcription and Translation? Moreover, both processes need a template to initiate.Furthermore, both processes have three major phases.Also, both are similarly essential for protein synthesis.Transcription and Translation are major steps of gene expression.What are the Similarities Between Transcription and Translation? However, since it is an RNA sequence, RNA polymerase adds uracil instead of thymine during the transcription. Hence, the resulting mRNA sequence becomes identical to the coding sequence. RNA polymerase enzyme reads the nucleotides of the coding sequence and adds correct complementary ribonucleotides and constructs the mRNA molecule, which contains the genetic code of the coding sequence. Non-coding sequence serves as the template in transcription since it is complementary to the coding sequence. Among the two strands of DNA in a gene, one serves as the coding sequence while the other is the non-coding sequence. RNA polymerase is the enzyme which catalyzes this process. Transcription occurs inside the nucleus of eukaryotes. It is the process of producing a mRNA molecule from a DNA template. Transcription is the first step of the gene expression. Side by Side Comparison – Transcription vs Translation in Tabular Form Similarities Between Transcription and Translationĥ. Transcription is the first step, and it is followed by the translation, which is the second major step of gene expression. Gene expression occurs via two major steps such as transcription and translation. Hence, gene expression is the process of synthesizing a protein molecule (gene product) from the genetic information hidden in the gene. In order to produce proteins, they undergo gene expression. They contain the genetic information (genetic code) to make proteins. The key difference between transcription and translation is that transcription refers to the process of producing a mRNA molecule for the DNA of a gene while translation refers to the process of synthesizing an amino acid sequence from the transcribed mRNA molecule.
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